Description

1-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid is a high-purity heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique fused pyrrolopyrimidine scaffold, which is a privileged structure in medicinal chemistry for designing potent and selective bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel kinase inhibitors, antiviral agents, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile chemical handle.
• Agrochemical Development: Serves as a precursor for novel active ingredients with herbicidal or fungicidal properties.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex molecules under cGMP or research-grade conditions.

Basic Information

Product Name	1-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid
CAS No.	1234615-86-1
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	1-Methyl-7H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid; 2-Carboxy-1-methyl-7H-pyrrolo[2,3-d]pyrimidine; 1-Methyl-1H-pyrrolo[2,3-d]pyrimidine-2-carboxylic acid; Pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, 1-methyl-7H-; 1234615-86-1; 1-Methyl-7H-pyrrolo[2,3-d]pyrimidin-2-oic acid
EINECS	Contact for details

Quality Control

Our 1-Methyl-7H-Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.