Description

6H-Pyrimido[4,5-B][1,4]Benzodiazepin-6-One, 5,11-Dihydro-2-[[2-Methoxy-4-(4-Methyl-1-Piperazinyl)Phenyl]Amino]-5,11-Dimethyl- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and preclinical studies requiring precise and reliable chemical entities. The CAS number for this product is 1234479-76-5.

Application

This specialized intermediate serves key roles in advanced chemical synthesis and research:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Oncology Drug Development: Employed in the research of potential kinase inhibitors or other targeted cancer therapies.
• CNS-Active Compound Synthesis: A key scaffold for developing potential treatments for neurological and psychiatric disorders.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific enzyme interactions or receptor binding.
• Custom Synthesis & Scale-Up: Serves as a starting material for contract manufacturing organizations (CMOs) producing custom APIs for clinical trials.

Basic Information

Product Name	6H-Pyrimido[4,5-B][1,4]Benzodiazepin-6-One, 5,11-Dihydro-2-[[2-Methoxy-4-(4-Methyl-1-Piperazinyl)Phenyl]Amino]-5,11-Dimethyl-
CAS No.	1234479-76-5
Molecular Formula	C24H29N7O2
Molecular Weight	447.54 g/mol
Synonyms	5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one; UNII-9FQ6S4B4Q2; 9FQ6S4B4Q2; CHEMBL3186472; BDBM50157857; AKOS025147324; AOB81117; 2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
EINECS	Contact for details

Quality Control

Our 6H-Pyrimido[4,5-B][1,4]Benzodiazepin-6-One derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.