Description

3-Fluoro-2-(Pyrrolidin-1-Yl)Aniline is a specialized fluorinated aniline derivative featuring a pyrrolidine substituent, making it a valuable building block in advanced organic synthesis. This compound is critical for medicinal chemistry research, particularly in the development of novel pharmaceutical candidates targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to introduce unique structural motifs that can modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug molecules, especially those requiring a fluorinated aniline core for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and amine functionality can improve efficacy and environmental profile.
• Ligand Synthesis: Employed in the creation of novel ligands for catalysis, where the pyrrolidine nitrogen can act as a coordinating site for transition metals.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized to build fluorescent tags or molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	3-Fluoro-2-(Pyrrolidin-1-Yl)Aniline
CAS No.	1233955-57-1
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	1-(2-Amino-6-fluorophenyl)pyrrolidine; 2-Fluoro-6-(pyrrolidin-1-yl)aniline; 3-Fluoro-2-(1-pyrrolidinyl)benzenamine; 3-Fluoro-2-pyrrolidin-1-ylaniline; Benzenamine, 3-fluoro-2-(1-pyrrolidinyl)-; 1233955-57-1
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Pyrrolidin-1-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown solid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.