Description

2-Fluoro-6-(Neopentyloxy)Aniline is a specialized aromatic amine derivative featuring a unique combination of fluorine substitution and a bulky neopentyloxy group. This structural motif makes it a valuable and versatile building block in advanced organic synthesis, particularly for creating complex molecules with tailored properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and charge-transporting compounds in electronic displays.
• Polymer Chemistry: Acts as a monomer or chain modifier for producing high-performance polymers with specific thermal or optical characteristics.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and colorants for high-value applications.
• Cross-Coupling Reactions: The aniline moiety makes it a suitable substrate for Buchwald-Hartwig amination and other palladium-catalyzed reactions.

Basic Information

Product Name	2-Fluoro-6-(Neopentyloxy)Aniline
CAS No.	1233955-46-8
Molecular Formula	C11H16FNO
Molecular Weight	197.25 g/mol
Synonyms	2-Fluoro-6-(2,2-dimethylpropoxy)aniline; 6-(Neopentyloxy)-2-fluoroaniline; 2-Fluoro-6-neopentyloxyaniline; Benzenamine, 2-fluoro-6-(2,2-dimethylpropoxy)-; 2-Fluoro-6-(2,2-dimethylpropoxy)benzenamine; 2-FA-6-NPOA; F-6-NPOA Aniline
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Neopentyloxy)Aniline is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.