Description

2-Fluoro-6-(Tetrahydro-2H-Pyran-4-Yloxy)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique aniline core substituted with both fluorine and a tetrahydropyranyloxy group. This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to synthesize novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides due to its fluorinated aniline structure.
• Chemical Synthesis: Employed in organic synthesis for introducing the 2-fluoro-6-(tetrahydropyran-4-yloxy)aniline moiety into more complex architectures.
• Ligand and Catalyst Preparation: Can be utilized in the development of specialized ligands for catalysis or as a precursor for functional materials.

Basic Information

Product Name	2-Fluoro-6-(Tetrahydro-2H-Pyran-4-Yloxy)Aniline
CAS No.	1233952-43-6
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	2-Fluoro-6-(tetrahydro-2H-pyran-4-yloxy)benzenamine; 4-((2-Amino-3-fluorophenoxy)methyl)tetrahydro-2H-pyran; 2-Fluoro-6-(oxan-4-yloxy)aniline; 2-Fluoro-6-(tetrahydropyran-4-yloxy)aniline; 2-Amino-3-fluoro-1-(tetrahydro-2H-pyran-4-yloxy)benzene; Benzenamine, 2-fluoro-6-(tetrahydro-2H-pyran-4-yloxy)-; 1233952-43-6
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Tetrahydro-2H-Pyran-4-Yloxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.