Description

Fmoc-D-β-Homotrp(Boc)-OH is a protected, non-natural amino acid derivative specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks to construct complex peptides with specific structural and functional properties. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic peptides and in academic settings for probing protein structure and function.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the Fmoc-strategy synthesis of peptides containing the non-proteinogenic amino acid D-β-homotryptophan.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Peptide Library Construction: Essential for creating diverse combinatorial peptide libraries for high-throughput screening in drug discovery campaigns.
• Bioconjugation & Probe Development: Serves as a precursor for synthesizing labeled peptides or peptide conjugates used in biochemical assays and diagnostic tools.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in peptide chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Fmoc-D-β-Homotrp(Boc)-OH
CAS No.	1233494-96-6
Molecular Formula	C34H36N2O6
Molecular Weight	568.66 g/mol
Synonyms	Fmoc-D-β-homotryptophan(Boc)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-β-homotryptophan N-tert-butoxycarbonyl; Fmoc-D-β-Hot(Boc)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-((tert-butoxycarbonyl)indolin-3-yl)propanoic acid; Nα-Fmoc-Nin-Boc-D-β-homotryptophan; Fmoc-D-β-Homotrp(t-Boc)-OH; D-β-Homotryptophan, Nα-Fmoc, Nin-Boc protected
EINECS	Contact for details

Quality Control

Our Fmoc-D-β-Homotrp(Boc)-OH is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.