Description

3-Bromo-4-Fluoro-5-Trifluoromethyl-Phenylamine is a high-value, multi-functional aromatic amine building block distinguished by its unique halogen and trifluoromethyl substitution pattern. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the fine-tuning of material characteristics and biological activity. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine and trifluoromethyl groups enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for specialty chemicals used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into polymer chains to impart specific properties like chemical resistance, thermal stability, or unique optical characteristics.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl and heterocyclic structures.

Basic Information

Product Name	3-Bromo-4-Fluoro-5-Trifluoromethyl-Phenylamine
CAS No.	1233026-11-3
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	3-Bromo-4-fluoro-5-(trifluoromethyl)aniline; 5-Amino-2-bromo-1-fluoro-3-(trifluoromethyl)benzene; 2-Bromo-1-fluoro-3-(trifluoromethyl)-5-aminobenzene; 3-Bromo-4-fluoro-5-trifluoromethylaniline; 3-Bromo-4-fluoro-α,α,α-trifluoro-m-toluidine; 3-Bromo-4-fluoro-5-(trifluoromethyl)benzenamine; 1233026-11-3; 3-Br-4-F-5-CF3-C6H2-NH2
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-5-Trifluoromethyl-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.