Description

2-Methyl-6-Piperidin-3-Yl-Pyrimidin-4-Ol Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1229625-11-9. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of potential new APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control.
• Academic Research: Employed in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	2-Methyl-6-Piperidin-3-Yl-Pyrimidin-4-Ol Dihydrochloride
CAS No.	1229625-11-9
Molecular Formula	C10H16N3O•2HCl
Molecular Weight	279.18 g/mol
Synonyms	2-Methyl-6-(piperidin-3-yl)pyrimidin-4-ol dihydrochloride; 4-Pyrimidinol, 2-methyl-6-(3-piperidinyl)-, dihydrochloride; 6-(3-Piperidinyl)-2-methyl-4-pyrimidinol dihydrochloride; 2-Methyl-6-(3-piperidyl)pyrimidin-4-ol dihydrochloride; 1229625-11-9; UNII-8KQ0K1W4VH; 8KQ0K1W4VH
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-Piperidin-3-Yl-Pyrimidin-4-Ol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.