Description

1-(3-Fluorophenyl)Cyclobutanamine Hydrochloride CAS NO 1228880-28-1 is a high-purity organic compound, specifically a fluorinated cyclobutylamine hydrochloride salt, valued for its role as a critical pharmaceutical intermediate and research chemical. Its unique structure makes it a versatile building block for medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material synthesis sectors seeking to incorporate a fluorinated cyclobutylamine moiety into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Employed in the development of advanced pesticides and herbicides where the fluorophenyl and cyclobutylamine groups confer specific biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(3-Fluorophenyl)Cyclobutanamine Hydrochloride
CAS No.	1228880-28-1
Molecular Formula	C10H13FN • HCl
Molecular Weight	201.68 g/mol (free base: 165.22 g/mol)
Synonyms	1-(3-Fluorophenyl)cyclobutanamine HCl; 3-Fluoro-α-cyclobutylbenzenemethanamine hydrochloride; 1-(3-Fluorophenyl)cyclobutan-1-amine hydrochloride; 3-Fluorophenyl cyclobutyl amine hydrochloride; 1-Amino-1-(3-fluorophenyl)cyclobutane hydrochloride; FCBA HCl; (3-Fluorophenyl)(cyclobutyl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)Cyclobutanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.