Description

3,4-Difluoro-2,6-Diiodophenol is a high-purity, multi-halogenated phenolic compound designed for advanced synthetic chemistry. This specialty intermediate is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and high-performance materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for its unique reactivity profile.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the fluorine and iodine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating halogenated aromatic cores essential in the manufacture of advanced electronic display materials.
• Polymer Modification: Employed to introduce halogenated phenolic units into polymer chains, imparting flame retardancy and altered thermal properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) due to the presence of two iodine atoms, enabling rapid diversification in medicinal chemistry.
• Ligand & Catalyst Development: Used to synthesize novel chelating ligands for metal catalysts used in asymmetric synthesis and industrial processes.

Basic Information

Product Name	3,4-Difluoro-2,6-Diiodophenol
CAS No.	1228093-47-7
Molecular Formula	C6H2F2I2O
Molecular Weight	397.88 g/mol
Synonyms	2,6-Diiodo-3,4-difluorophenol; Phenol, 3,4-difluoro-2,6-diiodo-; 3,4-Difluoro-2,6-diiodo-1-phenol; 2,6-Diiodo-3,4-difluoro-1-hydroxybenzene; 1-Hydroxy-2,6-diiodo-3,4-difluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluoro-2,6-Diiodophenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.