Description

4-(4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Morpholine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyrimidine core. This compound is of significant commercial importance for its role as a key building block in the synthesis of targeted kinase inhibitors and other bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small-molecule drugs targeting specific protein kinases.
• Oncology Research: Used in the R&D of potential anti-cancer agents, particularly those inhibiting JAK, ALK, or other relevant kinase pathways.
• Chemical Biology: Serves as a scaffold for creating chemical probes to study cellular signaling mechanisms and disease pathways.
• Process Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) under cGMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-(4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Morpholine
CAS No.	1227958-05-5
Molecular Formula	C10H11ClN4O
Molecular Weight	238.67 g/mol
Synonyms	4-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)morpholine; 2-Morpholino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2-morpholino-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidine; 1227958-05-5; UNII-9F7I8Y4J0F; 9F7I8Y4J0F
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-2-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.