Description

2-(4-Bromo-2-Fluorophenoxy)-4-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in the development of novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical industries for the creation of new drug candidates and crop protection agents, where its unique halogenated and trifluoromethylated structure offers significant advantages in modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine and bromine substituents.
• Material Science Precursor: Used in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Acts as a versatile intermediate for creating molecular probes and tool compounds used in biochemical and pharmacological research.

Basic Information

Product Name	2-(4-Bromo-2-Fluorophenoxy)-4-(Trifluoromethyl)Pyrimidine
CAS No.	1227955-13-6
Molecular Formula	C11H5BrF4N2O
Molecular Weight	337.07 g/mol
Synonyms	4-(Trifluoromethyl)-2-[(4-bromo-2-fluorophenoxy)]pyrimidine; 2-(4-Bromo-2-fluorophenoxy)-4-(trifluoromethyl)pyrimidine; Pyrimidine, 2-(4-bromo-2-fluorophenoxy)-4-(trifluoromethyl)-; 1227955-13-6; 4-Trifluoromethyl-2-(4-bromo-2-fluorophenoxy)pyrimidine; 2-(4-Bromo-2-fluoro-phenoxy)-4-trifluoromethyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Fluorophenoxy)-4-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.