Description

1-(4-{[4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Phenyl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its pyrimidine-based structure and trifluoromethyl functional group. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas where fluorinated heterocycles are of significant interest.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the pyrimidine moiety.
• Material Science: Serves as a precursor for specialty chemicals and functional materials requiring fluorinated aromatic systems.
• Academic & Contract Research: Employed in university and CRO laboratories for structure-activity relationship (SAR) studies and medicinal chemistry optimization.

Basic Information

Product Name	1-(4-{[4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Phenyl)Ethanone
CAS No.	1227954-94-0
Molecular Formula	C13H9F3N2O2
Molecular Weight	282.22 g/mol
Synonyms	1-[4-[[4-(Trifluoromethyl)pyrimidin-2-yl]oxy]phenyl]ethanone; 2-[4-Acetylphenoxy]-4-(trifluoromethyl)pyrimidine; 4'-Acetyl-2'-[4-(trifluoromethyl)pyrimidin-2-yloxy]acetophenone; CAS 1227954-94-0; TFMPOAP; 1-(4-((4-(Trifluoromethyl)pyrimidin-2-yl)oxy)phenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our production of 1-(4-{[4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy}Phenyl)Ethanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.