Description

2-Fluoro-4-(Trifluoromethoxy)Benzaldehyde, 97% is a high-purity fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethoxy substituents, is engineered to impart unique electronic and steric properties to target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties.
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced resins that require specific thermal and chemical resistance.
• Cross-Coupling Reactions: Acts as a versatile electrophile in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on exploring new fluorination strategies and novel heterocyclic compounds.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethoxy)Benzaldehyde, 97%
CAS No.	1227628-83-2
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	2-Fluoro-4-(trifluoromethoxy)benzaldehyde; 4-(Trifluoromethoxy)-2-fluorobenzaldehyde; 2-Fluoro-α,α,α-trifluoro-p-anisaldehyde; Benzaldehyde, 2-fluoro-4-(trifluoromethoxy)-; 1227628-83-2; 2-Fluoro-4-trifluoromethoxybenzaldehyde; 2-Fluoro-4-(trifluoromethoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethoxy)Benzaldehyde, 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the declared purity and impurity profile specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent levels is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.