Description

3,4-Dimethylthiophene-2-Sulfonyl Chloride is a high-value, reactive sulfonyl chloride derivative used as a key building block in advanced organic synthesis. This compound is critical for introducing the 3,4-dimethylthiophene-2-sulfonyl moiety, a versatile functional group in medicinal chemistry and materials science. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for creating sulfonamide-based molecules with targeted biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the thiophene-sulfonyl group can enhance efficacy and selectivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, conductive materials, or organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes or affinity labels for studying enzyme function and protein interactions.
• Ligand and Catalyst Development: Useful for constructing novel ligands for metal complexes or organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Item	Details
Product Name	3,4-Dimethylthiophene-2-Sulfonyl Chloride
CAS No.	1227608-07-2
Molecular Formula	C6H7ClO2S2
Molecular Weight	210.70 g/mol
Synonyms	2-Thiophenesulfonyl chloride, 3,4-dimethyl-; 3,4-Dimethyl-2-thiophenesulfonyl chloride; 3,4-Dimethylthiophene-2-sulfonyl chloride; 1227608-07-2; 3,4-Dimethylthiophene-2-sulfonchlorid; 3,4-Dimethyl-2-thienylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3,4-Dimethylthiophene-2-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.