Description

Methyl 5-Fluoropyrimidine-2-Carboxylate is a high-purity fluorinated pyrimidine derivative, a critical building block in modern synthetic organic chemistry. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require fluorinated pyrimidine cores for enhanced activity and selectivity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis and metal-catalyzed reactions.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	Methyl 5-Fluoropyrimidine-2-Carboxylate
CAS No.	1227575-47-4
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	5-Fluoropyrimidine-2-carboxylic acid methyl ester; Methyl 5-fluoropyrimidine-2-carboxylate; 2-Pyrimidinecarboxylic acid, 5-fluoro-, methyl ester; 5-Fluoro-2-pyrimidinecarboxylic acid methyl ester; Methyl 5-fluoro-2-pyrimidinecarboxylate; 1227575-47-4
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoropyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.