Description

Ethyl 5-Chloropyrimidine-2-Carboxylate is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, high-quality intermediate to construct complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Essential reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Used in the research and production of specialty polymers and advanced organic materials.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for custom molecule manufacturing.

Basic Information

Product Name	Ethyl 5-Chloropyrimidine-2-Carboxylate
CAS No.	1227571-82-5
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	5-Chloropyrimidine-2-carboxylic acid ethyl ester; Ethyl 5-chloro-2-pyrimidinecarboxylate; 2-Pyrimidinecarboxylic acid, 5-chloro-, ethyl ester; 5-Chloro-2-pyrimidinecarboxylic acid ethyl ester; Ethyl 5-chloropyrimidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloropyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.