Description

1-(3-Chloro-2-Fluorophenyl)Cyclopropanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropylamine-substituted aromatic ring system. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers seeking to incorporate its distinct structural motif into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new pesticides and herbicides, leveraging the bioactivity of the fluorinated phenylcyclopropylamine structure.
• Ligand Synthesis: Used in organometallic chemistry for the preparation of chiral ligands and catalysts in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Investigated as a monomer or additive for specialty polymers with tailored thermal or optical properties.

Basic Information

Product Name	1-(3-Chloro-2-Fluorophenyl)Cyclopropanamine
CAS No.	1227418-16-7
Molecular Formula	C9H9ClFN
Molecular Weight	185.62 g/mol
Synonyms	1-(3-Chloro-2-fluorophenyl)cyclopropanamine; 1-(3-Chloro-2-fluorophenyl)cyclopropan-1-amine; 3-Chloro-2-fluoro-α-(cyclopropylamino)toluene; Cyclopropanamine, 1-(3-chloro-2-fluorophenyl)-; 1227418-16-7; (3-Chloro-2-fluorophenyl)cyclopropylamine; 1-(3-Chloro-2-fluoro-phenyl)-cyclopropylamine
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-2-Fluorophenyl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.