Description

4-Chloro-7-(2,4-Dimethoxybenzyl)-5H-Pyrrolo[2,3-D]Pyrimidin-6(7H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing biochemical probes to study specific enzymatic pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant synthesis of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	4-Chloro-7-(2,4-Dimethoxybenzyl)-5H-Pyrrolo[2,3-D]Pyrimidin-6(7H)-One
CAS No.	1226804-67-6
Molecular Formula	C₁₅H₁₄ClN₃O₃
Molecular Weight	319.74 g/mol
Synonyms	4-Chloro-7-(2,4-dimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidin-6-one; 1226804-67-6; 4-Chloro-7-(2,4-dimethoxybenzyl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one; 4-Chloro-7-(2,4-dimethoxybenzyl)-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one; 7-(2,4-Dimethoxybenzyl)-4-chloro-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(2,4-Dimethoxybenzyl)-5H-Pyrrolo[2,3-D]Pyrimidin-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.