Description

4-Chloro-5-Methyl-5H-Pyrrolo[2,3-D]Pyrimidin-6(7H)-One is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific pyrrolopyrimidine scaffolds.
• Chemical Biology & Proteomics: Serves as a core structure for designing chemical probes and tool compounds to study biological pathways and protein function.
• Material Science Research: Investigated as a precursor for organic electronic materials and functional polymers due to its fused heterocyclic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and process scale-up projects for global clients.
• Academic Research: Utilized in university and institutional laboratories for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Chloro-5-Methyl-5H-Pyrrolo[2,3-D]Pyrimidin-6(7H)-One
CAS No.	1226804-06-3
Molecular Formula	C7H6ClN3O
Molecular Weight	183.59 g/mol
Synonyms	4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-6-one; 4-Chloro-5-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-6-one; 6(7H)-One, 4-chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-; 1226804-06-3; 4-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one; 4-Chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-6(7H)-one
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methyl-5H-Pyrrolo[2,3-D]Pyrimidin-6(7H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.