Description

2-(Methylthio)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1226776-81-3. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Oncology Research: Used in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Serves as a core scaffold for compounds targeting neurological disorders.
• Chemical Synthesis: Employed in academic and industrial laboratories for method development and novel heterocyclic chemistry.
• Process Chemistry: Utilized in scaling up synthetic routes for preclinical and clinical trial material production.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	2-(Methylthio)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Hydrochloride
CAS No.	1226776-81-3
Molecular Formula	C9H12N3S • HCl
Molecular Weight	245.74 g/mol
Synonyms	2-(Methylthio)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl; 2-(Methylsulfanyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 2-Methylsulfanyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride; 5,6,7,8-Tetrahydro-2-(methylthio)pyrido[3,4-d]pyrimidine hydrochloride; CAS 1226776-81-3
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.