Description

2-Propenamide, n-[3-[4-[[(1S)-2-Hydroxy-1-Phenylethyl]Amino]-6-Phenylfuro[2,3-D]Pyrimidin-5-Yl]Phenyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the research and development of targeted therapeutic agents, particularly in oncology and other specialized medical fields. It is essential for medicinal chemists and pharmaceutical manufacturers engaged in the synthesis of novel small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel furo[2,3-d]pyrimidine-based drug candidates for targeted therapies.
• Oncology Research: Used in the development of potential kinase inhibitors and other anti-cancer agents due to its specific molecular scaffold.
• Medicinal Chemistry R&D: Serves as a crucial precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed as a probe or reference standard in biochemical assays to study specific enzyme interactions and pathways.
• Custom Synthesis: Starting material for the contract manufacturing of specialized APIs (Active Pharmaceutical Ingredients) under cGMP conditions.

Basic Information

Product Name	2-Propenamide, n-[3-[4-[[(1S)-2-Hydroxy-1-Phenylethyl]Amino]-6-Phenylfuro[2,3-D]Pyrimidin-5-Yl]Phenyl]-
CAS No.	1226549-39-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-[3-[4-[[(1S)-2-Hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]-2-propenamide; (S)-N-(3-(4-((2-Hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)acrylamide; Advanced Furopyrimidine Intermediate; CAS 1226549-39-8; Acrylamide-based Pharmaceutical Intermediate; Phenylethylamino Furopyrimidine Derivative
EINECS	Contact for details

Quality Control

Our 2-Propenamide, n-[3-[4-[[(1S)-2-Hydroxy-1-Phenylethyl]Amino]-6-Phenylfuro[2,3-D]Pyrimidin-5-Yl]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.