Description

n-(4-Chloro-2-Pyrimidinyl)-2,3-Dimethyl-2H-Indazol-6-Amine is a high-purity pharmaceutical intermediate and research chemical with the CAS number 1226499-97-3. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing new therapeutic agents, especially within oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific enzyme interactions and pathways.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for custom synthesis and exploratory research projects.
• API Development: Employed in the early-stage development and scale-up processes for new Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	n-(4-Chloro-2-Pyrimidinyl)-2,3-Dimethyl-2H-Indazol-6-Amine
CAS No.	1226499-97-3
Molecular Formula	C15H15ClN6
Molecular Weight	314.77 g/mol
Synonyms	4-Chloro-N-(2,3-dimethyl-2H-indazol-6-yl)pyrimidin-2-amine; 2,3-Dimethyl-2H-indazol-6-amine, N-(4-chloro-2-pyrimidinyl)-; 1226499-97-3; 4-Chloro-2-((2,3-dimethyl-2H-indazol-6-yl)amino)pyrimidine; 6-Amino-2,3-dimethyl-2H-indazole, N-(4-chloro-2-pyrimidinyl) derivative; (4-Chloro-pyrimidin-2-yl)-(2,3-dimethyl-2H-indazol-6-yl)-amine
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-2-Pyrimidinyl)-2,3-Dimethyl-2H-Indazol-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.