Description

[1,1'-Biphenyl]-3-Amine, 4-Fluoro-3',4'-Dimethyl- is a high-purity, fluorinated biphenylamine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its biphenyl core for enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials, host materials, and other functional components in organic light-emitting diodes (OLEDs) and liquid crystal displays (LCDs).
• Polymer & Resin Modifier: Incorporated as a monomer or additive to impart specific thermal, optical, or mechanical properties to high-performance polymers and epoxy resins.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalytic systems due to its amine functionality and substituted biphenyl structure.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments with specific color fastness and light-absorption characteristics.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Amine, 4-Fluoro-3',4'-Dimethyl-
CAS No.	1225710-08-6
Molecular Formula	C14H14FN
Molecular Weight	215.27 g/mol
Synonyms	4-Fluoro-3',4'-dimethylbiphenyl-3-amine; 3-Amino-4'-fluoro-3',4-dimethyldiphenyl; 4'-Fluoro-3',4-dimethyldiphenyl-3-amine; 4-Fluoro-3',4'-dimethyl-[1,1'-biphenyl]-3-amine; 3',4'-Dimethyl-4-fluorobiphenyl-3-amine; 4-Fluoro-3',4'-dimethyl-1,1'-biphenyl-3-amine
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Amine, 4-Fluoro-3',4'-Dimethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.