Description

N2-(1-Oxododecyl)-D-Arginine is a chemically modified derivative of the D-enantiomer of the amino acid arginine, featuring a lauroyl (dodecanoyl) chain. This specific structural modification is crucial for enhancing lipophilicity and membrane permeability, making it a valuable synthetic intermediate. It is primarily sought after by research institutions and pharmaceutical developers engaged in advanced peptide synthesis and medicinal chemistry. The compound is instrumental in creating novel bioactive molecules with potential applications in therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based drugs and prodrugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to modify peptide properties like stability and bioavailability.
• Bioconjugation: Serves as a linker or modifier for attaching lipid chains to peptides or proteins to alter their pharmacokinetic profile.
• Cosmetic Peptide Synthesis: Potential raw material for synthesizing lipophilic anti-aging or skin-conditioning peptide actives.
• Biochemical Tool Development: Utilized in creating specialized probes or inhibitors for studying biological pathways.

Basic Information

Product Name	N2-(1-Oxododecyl)-D-Arginine
CAS No.	1225433-34-0
Molecular Formula	C18H35N5O3
Molecular Weight	369.51 g/mol
Synonyms	D-Arg(Lau); Lauroyl-D-arginine; Nα-Lauroyl-D-arginine; N2-Dodecanoyl-D-arginine; (R)-2-Amino-5-guanidino-N-(1-oxododecyl)pentanamide; D-Arg-C12; LA-D-Arg
EINECS	Contact for details

Quality Control

Our N2-(1-Oxododecyl)-D-Arginine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.