Description

2-Amino-5, 6, 7, 8-Tetrahydro-Pyrido[4, 3-D]Pyrimidine-4-Carboxylic Acid Amide is a high-purity heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical synthesis. This compound is valued for its role as a sophisticated intermediate in the development of novel therapeutic agents, particularly kinase inhibitors. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially for targeted cancer therapies.
• Kinase Inhibitor Synthesis: Central scaffold for constructing potent and selective kinase inhibitors, a major class of oncology and anti-inflammatory drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs within academic and industrial R&D labs.
• Process Development: Serves as a starting material or advanced intermediate in scaling up API (Active Pharmaceutical Ingredient) manufacturing processes under GMP conditions.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis: Basis for the custom manufacturing of specialized derivatives and analogs for client-specific research projects.

Basic Information

Product Name	2-Amino-5, 6, 7, 8-Tetrahydro-Pyrido[4, 3-D]Pyrimidine-4-Carboxylic Acid Amide
CAS No.	1223748-53-5
Molecular Formula	C8H11N5O
Molecular Weight	193.21 g/mol
Synonyms	2-Amino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-4-carboxamide; 4-Pyrimidinecarboxamide, 2-amino-5,6,7,8-tetrahydro-3H-pyrido[4,3-d]pyrimidine; 2-Amino-4-carbamoyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; THPP-Carboxamide; Pyrido[4,3-d]pyrimidine-4-carboxamide derivative; 1223748-53-5; CAS 1223748-53-5
EINECS	Contact for details

Quality Control

Our 2-Amino-5, 6, 7, 8-Tetrahydro-Pyrido[4, 3-D]Pyrimidine-4-Carboxylic Acid Amide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ICH guidelines for impurities and can provide material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.