Description

Fmoc-4-(3-Methoxyphenyl)-L-Phenylalanine is a high-purity, non-natural amino acid derivative designed for solid-phase peptide synthesis (SPPS). This compound is a critical building block for researchers and manufacturers developing complex peptides and peptidomimetics with specific aromatic modifications. It is essential for pharmaceutical R&D, particularly in creating therapeutic peptides, diagnostic agents, and advanced materials where precise structural control is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs and bioactive compounds.
• Peptidomimetic Design: Incorporates a modified aromatic side chain to enhance binding affinity, stability, or pharmacokinetic properties of peptide analogs.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged peptides used in biochemical assays and imaging studies.
• Material Science: Can be utilized in the synthesis of peptide-conjugated polymers or surface coatings.
• Academic & Contract Research: A vital reagent for universities and CROs conducting cutting-edge research in medicinal chemistry and biochemistry.

Basic Information

Product Name	Fmoc-4-(3-Methoxyphenyl)-L-Phenylalanine
CAS No.	1223105-50-7
Molecular Formula	C31H27NO5
Molecular Weight	493.55 g/mol
Synonyms	Fmoc-4-(3-methoxyphenyl)-L-Phe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-(3-methoxyphenyl)-L-phenylalanine; Fmoc-L-4-(3-Methoxyphenyl)phenylalanine; Fmoc-3'-Methoxy-L-biphenylalanine; Fmoc-4-(m-Methoxyphenyl)-L-phenylalanine; N-Fmoc-4'-(3-methoxyphenyl)-L-phenylalanine; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[4-(3-methoxyphenyl)phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-4-(3-Methoxyphenyl)-L-Phenylalanine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the high standards required for sensitive peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.