Description

4-Bromo-3-(Trifluoromethoxy)Benzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. Its molecular structure, featuring both bromo and trifluoromethoxy substituents, makes it a critical intermediate for synthesizing complex molecules with tailored electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce these valuable functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its electron-withdrawing groups can fine-tune HOMO/LUMO energy levels.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	4-Bromo-3-(Trifluoromethoxy)Benzaldehyde
CAS No.	1221716-04-6
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	4-Bromo-3-(trifluoromethoxy)benzaldehyde; 3-Trifluoromethoxy-4-bromobenzaldehyde; Benzaldehyde, 4-bromo-3-(trifluoromethoxy)-; 4-Bromo-α,α,α-trifluoro-m-anisaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.