Description

4-(5-Chloro-1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its role as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing novel treatments for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel kinase inhibitors for oncology research.
• Biochemical Research: Used as a reference standard and a tool compound in enzymatic and cellular assays to study biological pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	4-(5-Chloro-1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Pyrimidin-2-Amine
CAS No.	1221153-82-7
Molecular Formula	C14H14ClN5
Molecular Weight	287.75 g/mol
Synonyms	4-(5-Chloro-1-isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine; 4-(5-Chloro-1-propan-2-ylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine; 1221153-82-7; 5-Chloro-1-isopropyl-3-(2-aminopyrimidin-4-yl)-1H-pyrrolo[2,3-c]pyridine; Pyrrolo[2,3-c]pyridine, 4-(5-chloro-1-isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 4-(5-Chloro-1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.