Description

4-Chloro-Pyrido[3,4-D]Pyrimidine-2-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block and key synthetic intermediate in modern organic chemistry. This compound is essential for research and development in medicinal chemistry, particularly for constructing complex molecular scaffolds with targeted biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the design and creation of molecular probes for studying enzyme function and cellular signaling.
• Fine Chemical Synthesis: A valuable building block for constructing complex heterocyclic compounds in custom synthesis and process development.

Basic Information

Product Name	4-Chloro-Pyrido[3,4-D]Pyrimidine-2-Carboxylic Acid Methyl Ester
CAS No.	1220039-65-5
Molecular Formula	C10H6ClN3O2
Molecular Weight	235.63 g/mol
Synonyms	Methyl 4-chloropyrido[3,4-d]pyrimidine-2-carboxylate; 4-Chloro-2-(methoxycarbonyl)pyrido[3,4-d]pyrimidine; 4-Chloro-2-carbomethoxypyrido[3,4-d]pyrimidine; 1220039-65-5; Pyrido[3,4-d]pyrimidine-2-carboxylic acid, 4-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-Pyrido[3,4-D]Pyrimidine-2-Carboxylic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.