Description

4-Fluoro-1H-Indole-3-Carboxylic Acid Methyl Ester is a high-value fluorinated indole derivative, a crucial building block in modern organic synthesis. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules with tailored biological and physical properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science Precursor: Serves as a starting material for creating specialized organic electronic materials and functional dyes.
• Chemical Biology Probe: Employed in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	4-Fluoro-1H-Indole-3-Carboxylic Acid Methyl Ester
CAS No.	1220039-52-0
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	Methyl 4-Fluoro-1H-indole-3-carboxylate; 4-Fluoroindole-3-carboxylic Acid Methyl Ester; 1H-Indole-3-carboxylic acid, 4-fluoro-, methyl ester; 4-Fluoro-1H-indole-3-carboxylic acid methyl ester; Methyl 4-fluoro-1H-indole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Indole-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality systems are designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.