Description

2-Cyclopropyl-6,7-Dihydro-5H-Pyrrolo-[3,4-D]Pyrimidin-4-Ol CAS NO 1220038-59-4 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. Its complex bicyclic structure makes it a critical building block for the synthesis of novel, small-molecule active pharmaceutical ingredients (APIs). This compound is primarily required by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs, particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of targeted kinase inhibitors and other biologically active molecules.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization to develop new therapeutic candidates.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific enzyme functions and biological pathways in cellular assays.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for fundamental research on heterocyclic chemistry and novel synthetic methodologies.

Basic Information

Product Name	2-Cyclopropyl-6,7-Dihydro-5H-Pyrrolo-[3,4-D]Pyrimidin-4-Ol
CAS No.	1220038-59-4
Molecular Formula	C9H11N3O
Molecular Weight	177.20 g/mol
Synonyms	2-Cyclopropyl-4-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine; 4-Pyrimidinol, 2-cyclopropyl-5,6,7,7a-tetrahydro-3aH-pyrrolo[3,4-d]pyrimidine; 2-Cyclopropyl-5,6,7,7a-tetrahydro-3aH-pyrrolo[3,4-d]pyrimidin-4-ol; 1220038-59-4; Pyrrolopyrimidin-4-ol derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopropyl-6,7-Dihydro-5H-Pyrrolo-[3,4-D]Pyrimidin-4-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing purity, impurities, and analytical methods (e.g., HPLC, NMR) are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.