Description

4-Chloro-6-(3-Pyrrolidinylmethoxy)Pyrimidinehydrochloride is a high-purity pyrimidine derivative building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition and other therapeutic pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under GMP conditions.
• Bioconjugation & Probe Synthesis: Useful for creating chemical probes for biological target identification and validation.
• Custom Synthesis: Employed by fine chemical manufacturers for producing client-specific advanced intermediates.

Basic Information

Product Name	4-Chloro-6-(3-Pyrrolidinylmethoxy)Pyrimidinehydrochloride
CAS No.	1220038-29-8
Molecular Formula	C9H13ClN3O•HCl
Molecular Weight	252.13 g/mol
Synonyms	4-Chloro-6-[(3-pyrrolidinyl)methoxy]pyrimidine hydrochloride; 4-Chloro-6-(pyrrolidin-3-ylmethoxy)pyrimidine HCl; 4-Chloro-6-(3-pyrrolidinylmethoxy)pyrimidine HCl; 1220038-29-8; Pyrrolidin-3-ylmethoxy-pyrimidine derivative; 6-(3-Pyrrolidinylmethoxy)-4-chloropyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.