Description

2-Ethyl-6,7-Dihydro-5H-Pyrrolo-[3,4-D]Pyrimidin-4-Ol is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Biochemical Tool Compound: Serves as a core scaffold for developing probes to study specific enzyme pathways and biological mechanisms.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up and cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	2-Ethyl-6,7-Dihydro-5H-Pyrrolo-[3,4-D]Pyrimidin-4-Ol
CAS No.	1220030-37-4
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	2-Ethyl-4-hydroxy-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine; 4-Hydroxy-2-ethyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine; 2-Ethyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-4-one (tautomer); 2-Ethyl-6,7-dihydro-4H-pyrrolo[3,4-d]pyrimidin-4-one; 1220030-37-4; Pyrrolo[3,4-d]pyrimidin-4-ol, 2-ethyl-6,7-dihydro-5H-
EINECS	Contact for details

Quality Control

Our 2-Ethyl-6,7-Dihydro-5H-Pyrrolo-[3,4-D]Pyrimidin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.