Description

6-Chloro-n-Isobutylpyrimidin-4-Amine is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands used in catalytic systems.

Basic Information

Product Name	6-Chloro-n-Isobutylpyrimidin-4-Amine
CAS No.	1220028-08-9
Molecular Formula	C8H12ClN3
Molecular Weight	185.65 g/mol
Synonyms	4-Amino-6-chloro-N-isobutylpyrimidine; 6-Chloro-N-(2-methylpropyl)pyrimidin-4-amine; 6-Chloro-N-isobutyl-4-pyrimidinamine; 6-Chloro-N-isobutylpyrimidin-4-ylamine; 4-Pyrimidinamine, 6-chloro-N-(2-methylpropyl)-; 1220028-08-9; 6-Chloro-N-isobutyl-4-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 6-Chloro-n-Isobutylpyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.