Description

[1,1'-Biphenyl]-3-Amine, 2',4,4'-Trifluoro- is a high-purity, multi-fluorinated biphenylamine derivative, a key advanced intermediate in modern synthetic chemistry. Its value lies in its unique trifluorinated biphenyl scaffold, which imparts desirable electronic and steric properties for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a critical building block for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the stability and bioavailability often conferred by fluorine atoms.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the development of specialty electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Science: Acts as a monomer or chain modifier in the synthesis of high-performance polymers, such as polyamides and polyimides, for advanced engineering applications.
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a sophisticated synthon in cross-coupling reactions and other catalytic processes to create complex organic architectures.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Amine, 2',4,4'-Trifluoro-
CAS No.	1219622-36-2
Molecular Formula	C12H7F3N2
Molecular Weight	236.20 g/mol
Synonyms	2',4,4'-Trifluoro-[1,1'-biphenyl]-3-amine; 3-Amino-2',4,4'-trifluorobiphenyl; 2',4,4'-Trifluorobiphenyl-3-amine; 2',4,4'-Trifluoro-3-aminobiphenyl; 2',4,4'-Trifluoro-1,1'-biphenyl-3-amine; (2',4,4'-Trifluoro-[1,1'-biphenyl]-3-yl)amine
EINECS	Contact for details

Quality Control

Our production of [1,1'-Biphenyl]-3-Amine, 2',4,4'-Trifluoro- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP requirements for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.