Description

Fmoc-6-Methyl-Dl-Tryptophan CAS NO 1219150-44-3 is a protected, non-natural amino acid derivative essential for advanced peptide synthesis. Its core value lies in providing a versatile building block for constructing complex peptides with enhanced stability and specific functionality. This compound is critically needed by research institutions and pharmaceutical developers working on novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, stepwise assembly of custom peptide sequences in drug discovery pipelines.
• Peptidomimetic Drug Development: Used to incorporate modified tryptophan analogs into peptide backbones to enhance metabolic stability, bioavailability, and receptor binding affinity.
• Bioconjugation and Probe Synthesis: Serves as a precursor for creating fluorescently labeled or affinity-tagged peptides for diagnostic and imaging applications.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic and Industrial Research: Fundamental reagent for studying protein-protein interactions, enzyme mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	Fmoc-6-Methyl-Dl-Tryptophan
CAS No.	1219150-44-3
Molecular Formula	C₂₇H₂₄N₂O₄
Molecular Weight	440.49 g/mol
Synonyms	Fmoc-6-Me-DL-Trp-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-6-methyl-DL-tryptophan; (RS)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-methyl-1H-indol-3-yl)propanoic acid; Fmoc-6-methyltryptophan; 6-Methyl-DL-tryptophan Fmoc derivative; N-Fmoc-6-methyl-DL-tryptophan; Fmoc-6-methyl-DL-Trp; Fmoc-6-methyltryptophan racemic mixture
EINECS	Contact for details

Quality Control

Our Fmoc-6-Methyl-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.