Description

2-(3-Methoxypropylamino)Pyrimidine-5-Boronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. This compound is valued for its role in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules. The CAS number for this product is 1218789-31-1.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Cross-Coupling Reactions: Specifically designed as a boronic ester for efficient and selective Suzuki-Miyaura cross-coupling to form carbon-carbon bonds.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for drug discovery campaigns.

Basic Information

Item	Detail
Product Name	2-(3-Methoxypropylamino)Pyrimidine-5-Boronic Acid, Pinacol Ester
CAS No.	1218789-31-1
Molecular Formula	C14H24BN3O3
Molecular Weight	293.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(3-methoxypropyl)pyrimidin-2-amine; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine, N-(3-methoxypropyl)-; 2-[(3-Methoxypropyl)amino]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-(3-Methoxypropylamino)pyrimidine-5-boronic acid pinacol ester; Boronic acid, B-[2-[(3-methoxypropyl)amino]-5-pyrimidinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-(3-Methoxypropylamino)Pyrimidine-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in regulated research and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.