Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-β-Homothreonine(Otbu) is a specialized, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the construction of complex peptides and peptidomimetics. It is primarily utilized in pharmaceutical R&D, particularly in the development of novel therapeutic agents and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected D-β-homothreonine derivative for the controlled assembly of custom peptide sequences.
• Pharmaceutical Intermediates: Used in the research and development of new drug candidates, including enzyme inhibitors and receptor ligands.
• Peptidomimetic Design: Enables the synthesis of non-natural peptide analogs with enhanced stability and biological activity for medicinal chemistry applications.
• Bioconjugation: Acts as a specialized linker or spacer molecule in the creation of peptide-drug conjugates and other bioconjugates.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides used as tools for studying biological processes and protein interactions.
• Academic and Industrial R&D: A valuable reagent for research laboratories and fine chemical companies focused on peptide science and novel biomolecules.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-β-Homothreonine(Otbu)
CAS No.	1217837-63-2
Molecular Formula	C24H27NO6
Molecular Weight	425.48 g/mol
Synonyms	Fmoc-D-β-homothreonine(OtBu)-OH; Fmoc-D-β-HomoThr(OtBu)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-β-homothreonine tert-butyl ester; (2R)-3-[(2-Methylpropan-2-yl)oxy]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid; D-β-Homothreonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1,1-dimethylethyl ester; Fmoc-D-β-homo-Thr(OtBu)-OH; Fmoc-D-β-homothreonine(OtBu)-OH
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-β-Homothreonine(Otbu) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.