Description

n-Biotinyl-6-Amino-2-Naphthoic Acid CAS NO 1217755-61-7 is a high-purity, biotin-conjugated naphthoic acid derivative designed for advanced research and development. This compound serves as a critical building block and labeling reagent in the synthesis of biotinylated probes and targeted molecular conjugates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications requiring high-affinity binding to avidin or streptavidin.

Application

• Bioconjugation & Probe Synthesis: A key intermediate for creating biotin-labeled peptides, proteins, antibodies, and oligonucleotides for detection and purification systems.
• Diagnostic Assay Development: Used in the manufacturing of components for ELISA, lateral flow assays, and other immunoassays that leverage the biotin-streptavidin interaction for signal amplification.
• Drug Discovery & Target Identification: Employed in the synthesis of chemical probes for activity-based protein profiling (ABPP), pull-down assays, and cellular imaging to study protein function and localization.
• Affinity Chromatography: Serves as a linker for immobilizing ligands onto solid supports to create affinity columns for the purification of biomolecules.
• Material Science & Surface Functionalization: Used to introduce biotin groups onto nanoparticles, polymers, and biosensor surfaces for creating smart, responsive materials.

Basic Information

Product Name	n-Biotinyl-6-Amino-2-Naphthoic Acid
CAS No.	1217755-61-7
Molecular Formula	C21H23N3O4S
Molecular Weight	413.49 g/mol
Synonyms	6-[(5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl)amino]-2-naphthoic Acid; Biotin-6-Amino-2-Naphthoic Acid; Biotinyl-6-A-2-NA; N-Biotinyl-6-Amino-2-Naphthoic Acid; 6-Amino-2-naphthoic acid biotin conjugate; Biotinylated 6-Amino-2-Naphthoic Acid; 6-Amino-2-naphthoic acid N-biotinamide
EINECS	Contact for details

Quality Control

Our n-Biotinyl-6-Amino-2-Naphthoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.