Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-4-Acetylphe is a specialized amino acid derivative, specifically an N-Fmoc-protected derivative of D-4-acetylphenylalanine, designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemical control and side-chain functionality in their synthetic sequences. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected building block for the automated synthesis of complex peptides.
• Pharmaceutical Research: Incorporation into peptide drug candidates to introduce ketone functionality for bioconjugation or structural modification.
• Chemical Biology Probes: Synthesis of labeled peptides for studying protein-protein interactions and enzyme activity.
• Material Science: Development of functionalized peptide-based polymers and biomaterials.
• Antibody-Drug Conjugate (ADC) Development: Used to create site-specifically modified peptide linkers for payload attachment.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-4-Acetylphe
CAS No.	1217751-18-2
Molecular Formula	C27H23NO5
Molecular Weight	441.48 g/mol
Synonyms	Fmoc-D-4-Acetylphenylalanine-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-acetyl-D-phenylalanine; Fmoc-D-Phe(4-Ac)-OH; Nα-Fmoc-4-acetyl-D-phenylalanine; Fmoc-4-Acetyl-D-Phe-OH; (2R)-2-[(9H-fluoren-9-ylmethoxy)formamido]-3-[4-(acetyl)phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-4-Acetylphe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.