Description

(2R)-2-Amino-3-(3-Carbamoylphenyl)Propanoic Acid is a chiral, non-natural amino acid derivative featuring a phenylalanine backbone substituted with a carbamoyl group at the meta position. This compound serves as a critical pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and peptidomimetics.
• Drug Discovery Research: Used as a constrained amino acid analog in medicinal chemistry for structure-activity relationship (SAR) studies.
• Peptide Synthesis: Serves as a specialized building block for the solid-phase and solution-phase synthesis of modified peptides.
• Chemical Biology Probes: Incorporation into probes and inhibitors to study enzyme function and protein-protein interactions.
• Agrochemical Research: Potential intermediate in the development of novel, chiral crop protection agents.
• Academic & Contract Research: Fundamental research reagent in universities and CROs for developing new synthetic methodologies.

Basic Information

Product Name	(2R)-2-Amino-3-(3-Carbamoylphenyl)Propanoic Acid
CAS No.	1217747-36-8
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	(R)-2-Amino-3-(3-carbamoylphenyl)propanoic acid; (R)-3-Amino-3-(3-carbamoylphenyl)propionic acid; D-3-Carbamoylphenylalanine; (2R)-2-Azanyl-3-(3-carbamoylphenyl)propanoic acid; (R)-β-3-Carbamoylphenylalanine; (R)-3-(3-Carbamoylphenyl)alanine; (R)-m-Carbamoylphenylalanine; BOC-D-3-Carbamoylphenylalanine (protected form precursor)
EINECS	Contact for details

Quality Control

Our production of (2R)-2-Amino-3-(3-Carbamoylphenyl)Propanoic Acid adheres to stringent in-process controls and final release testing to ensure high chiral purity and chemical integrity. Each batch is analyzed via advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.