Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2-Methyl-4-Fluorophe CAS NO 1217744-26-7 is a specialized, high-purity amino acid derivative used as a key building block in advanced organic synthesis. This compound is critical for ensuring the precise stereochemistry and functional group integrity required in complex pharmaceutical and peptide research. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and oncological pathways.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid derivative to incorporate specific fluorinated and methylated side chains into peptide sequences.
• Proteomics Research: Serves as a building block for creating custom peptides and peptide mimetics used in drug discovery, structure-activity relationship (SAR) studies, and biochemical assays.
• Chemical Biology Tool: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and labeled compounds for mechanistic studies and diagnostic applications.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2-Methyl-4-Fluorophe
CAS No.	1217744-26-7
Molecular Formula	C25H22FNO4
Molecular Weight	419.45 g/mol
Synonyms	Fmoc-D-2-Me-4-F-Phe-OH; Fmoc-D-2-methyl-4-fluorophenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-2-methyl-4-fluorophenylalanine; D-Fmoc-2-methyl-4-fluorophenylalanine; (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(2-methyl-4-fluorophenyl)propanoic acid; Fmoc-D-2-Me-4-F-Phe; Nα-Fmoc-D-2-methyl-4-fluorophenylalanine
EINECS	Contact for details

Quality Control

Our production of (9H-Fluoren-9-Yl)Methoxy]Carbonyl D-2-Methyl-4-Fluorophe adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. The material is manufactured under controlled conditions suitable for research and pharmaceutical development. Certificates of Analysis (COA) are provided with each batch, detailing key parameters such as chiral purity, chemical purity, and identity confirmation. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.