Description

Fmoc-R-Amba-Oh CAS NO 1217711-57-3 is a high-purity, protected amino acid derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled and efficient assembly of complex peptide sequences, particularly those requiring specific side-chain protection strategies. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries engaged in developing novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential assembly of custom peptides.
• Pharmaceutical Research & Development: Used in the synthesis of peptide drug candidates, including hormone analogs and enzyme inhibitors.
• Combinatorial Chemistry: Serves as a key monomer for creating diverse peptide libraries for high-throughput screening.
• Bioconjugation: Facilitates the site-specific modification of peptides for labeling or coupling to other molecules (e.g., proteins, polymers, surfaces).
• Peptide Mimetic Development: Employed in the synthesis of peptidomimetics where the Amba scaffold is integral to the structure-activity relationship.
• Academic & Institutional Research: A standard reagent for studies in biochemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	Fmoc-R-Amba-Oh
CAS No.	1217711-57-3
Molecular Formula	C₂₀H₂₁NO₅
Molecular Weight	355.39 g/mol
Synonyms	Fmoc-4-Amino-3-(methoxycarbonyl)benzoic acid; Fmoc-4-Amino-3-(carbomethoxy)benzoic acid; Fmoc-4-Amino-m-phthalic acid monomethyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-amino-3-(methoxycarbonyl)benzoic acid; Fmoc-4-Amba-OH; Fmoc-protected 4-amino-3-methoxycarbonylbenzoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-R-Amba-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.