Description

N,n-Bis(Ethylmethanethiosulfonate) Biotinamide is a specialized biotin derivative functionalized with ethyl methanethiosulfonate groups, designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring precise, covalent attachment of biotin tags to proteins, peptides, or other biomolecules under controlled conditions. It is primarily utilized in the pharmaceutical, diagnostic, and life science research sectors for developing targeted assays, affinity purification systems, and novel therapeutic conjugates.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and peptides with biotin tags to create probes for detection and purification.
• Diagnostic Kit Development: A key intermediate in the synthesis of components for ELISA, lateral flow assays, and other immunoassay platforms.
• Affinity Chromatography Ligand Synthesis: Used to functionalize solid supports (e.g., agarose beads) for streptavidin/avidin-based purification columns.
• Chemical Biology Research: Enables the study of protein-protein interactions, cellular localization, and biomolecular trafficking through biotin-streptavidin technology.
• ADC (Antibody-Drug Conjugate) Development: Serves as a potential linker-payload component in the research phase of targeted cancer therapies.
• Molecular Probe Synthesis: For creating highly sensitive detection reagents used in fluorescence imaging, flow cytometry, and microscopy.

Basic Information

Item	Detail
Product Name	N,n-Bis(Ethylmethanethiosulfonate) Biotinamide
CAS No.	1217607-38-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotinamide, N,N-bis(ethyl methanethiosulfonate); Biotin-Ethyl Methanethiosulfonate Conjugate; Biotin-MTS Reagent; (+)-Biotin N,N-bis(ethyl methanethiosulfonate); Biotin Thiol-reactive Labeling Reagent; Biotinylation Reagent; 5-[(3aS,4S,6aR)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N,N-bis(ethylsulfonylmethanethioyl)pentanamide
EINECS	Contact for details

Quality Control

Our N,n-Bis(Ethylmethanethiosulfonate) Biotinamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.