Description

(Alphar)-3-Chloro-2-Fluoro-α-Methylbenzenemethanamine is a high-purity chiral amine building block of significant importance in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules with precise stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure herbicides and pesticides for enhanced efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry and process chemistry optimization.

Basic Information

Item	Details
Product Name	(Alphar)-3-Chloro-2-Fluoro-α-Methylbenzenemethanamine
CAS No.	1217449-55-2
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	(R)-1-(3-Chloro-2-fluorophenyl)ethanamine; (R)-3-Chloro-2-fluoro-α-methylbenzylamine; (R)-1-(3-Chloro-2-fluorophenyl)ethylamine; (αR)-3-Chloro-2-fluoro-α-methylbenzenemethanamine; (Alphar)-1-(3-Chloro-2-fluorophenyl)ethanamine; (R)-1-(3-Chloro-2-fluorophenyl)ethan-1-amine; (R)-3-Chloro-2-fluoro-α-methylbenzylamine; (R)-3-Chloro-2-fluoro-α-methylbenzeneethanamine
EINECS	Contact for details

Quality Control

Our (Alphar)-3-Chloro-2-Fluoro-α-Methylbenzenemethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.