Description

Furylacryloylphenylalanylglycylglycine CAS NO 1217441-68-3 is a specialized synthetic peptide derivative, primarily utilized as a high-purity biochemical reagent. This compound is valued for its role as a specific and sensitive substrate in enzymatic research and diagnostic assay development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and in-vitro diagnostics sectors who require precise tools for studying protease activity and enzyme kinetics.

Application

• Protease/Enzyme Substrate: A critical reagent for the study and quantification of specific proteolytic enzymes, including furin and related proprotein convertases.
• Biochemical Research: Used in kinetic assays, inhibitor screening, and mechanistic studies to understand enzyme function and regulation.
• Diagnostic Kit Development: Serves as a key component in the formulation of chromogenic or fluorogenic assay kits for clinical and research diagnostics.
• Pharmaceutical R&D: Employed in drug discovery pipelines targeting proteases, aiding in the identification and validation of novel therapeutic candidates.
• Quality Control Testing: Used as a reference standard in the quality assurance of enzyme preparations and diagnostic reagents.

Basic Information

Product Name	Furylacryloylphenylalanylglycylglycine
CAS No.	1217441-68-3
Molecular Formula	C24H24N4O7
Molecular Weight	480.47 g/mol
Synonyms	FAPPG; Furylacryloyl-Phe-Gly-Gly; 2-Furylacryloyl-Phenylalanyl-Glycyl-Glycine; (2E)-3-(2-Furanyl)-N-[(2S)-1-[[2-[(2-Aminoacetyl)amino]acetyl]amino]-3-phenyl-1-oxopropan-2-yl]-2-propenamide; Furin Substrate; Protease Substrate FAPPG
EINECS	Contact for details

Quality Control

Our Furylacryloylphenylalanylglycylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.