Description

1-(Pyrimidin-5-Yl)Cyclopropan-1-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropane-pyrimidine hybrid scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for oncology and central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained cyclopropane ring.
• Kinase Inhibitor Synthesis: Serves as a core fragment in the construction of potential kinase inhibitors, targeting various disease pathways.
• Agrochemical Research: Employed in the discovery of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring this specific amine-functionalized heterocycle.

Basic Information

Product Name	1-(Pyrimidin-5-Yl)Cyclopropan-1-Amine
CAS No.	1217340-83-4
Molecular Formula	C7H9N3
Molecular Weight	135.17 g/mol
Synonyms	1-(Pyrimidin-5-yl)cyclopropanamine; 5-(1-Aminocyclopropyl)pyrimidine; 1-Amino-1-(5-pyrimidinyl)cyclopropane; Cyclopropanamine, 1-(5-pyrimidinyl)-; 1-(Pyrimidin-5-yl)cyclopropylamine; 1-(5-Pyrimidyl)cyclopropanamine
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-5-Yl)Cyclopropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.