Description

3-Fluoro-5-(Trifluoromethyl)Benzene-1,2-Diamine is a high-purity, multi-fluorinated aromatic diamine building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents adjacent to the amine groups, makes it a critical intermediate for creating novel materials with tailored electronic and physicochemical properties. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring enhanced metabolic stability, lipophilicity, and chemical resistance.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics where fluorine substitution is advantageous.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the trifluoromethyl group to improve biological activity and environmental stability.
• Specialty Polymer Precursor: Serves as a monomer or cross-linking agent in the synthesis of high-performance polyimides, polyamides, and epoxy resins for electronics, aerospace, and coatings that demand exceptional thermal and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chelating ligands for catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: A valuable precursor for developing organic semiconductors, liquid crystals, and other functional materials where fluorination modulates electronic properties.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-value applications.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Benzene-1,2-Diamine
CAS No.	1217303-38-2
Molecular Formula	C7H6F4N2
Molecular Weight	194.13 g/mol
Synonyms	3-Fluoro-5-(trifluoromethyl)-1,2-benzenediamine; 3-Fluoro-5-(trifluoromethyl)benzene-1,2-diyldiamine; 1,2-Diamino-3-fluoro-5-(trifluoromethyl)benzene; 2-Fluoro-6-amino-4-(trifluoromethyl)aniline; 3-Fluoro-5-trifluoromethyl-o-phenylenediamine; 3-Fluoro-5-(trifluoromethyl)-o-phenylenediamine; 1217303-38-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Benzene-1,2-Diamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong oxidizing agents, acids, and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.