Description

4-Pyrimidinecarboxylic Acid, 2-(3-Chlorophenyl)- is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for advanced research and development in medicinal chemistry, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly for applications in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-Pyrimidinecarboxylic Acid, 2-(3-Chlorophenyl)-
CAS No.	1216604-60-2
Molecular Formula	C11H7ClN2O2
Molecular Weight	234.64 g/mol
Synonyms	2-(3-Chlorophenyl)pyrimidine-4-carboxylic acid; 2-(3-Chlorophenyl)-4-pyrimidinecarboxylic acid; 2-(3-Chlorophenyl)pyrimidine-4-carboxylate; 2-(m-Chlorophenyl)pyrimidine-4-carboxylic acid; 4-Carboxy-2-(3-chlorophenyl)pyrimidine; 1216604-60-2; 2-(3-Chlorophenyl)-4-carboxypyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Pyrimidinecarboxylic Acid, 2-(3-Chlorophenyl)- adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.